Ras association domain-containing protein 4 (RASSF4)
Homo sapiens — UniProt Q9H2L5
Data last refreshed: (UniProt release unknown)
Key facts
Ras association domain-containing protein 4 (RASSF4) is a protein from Homo sapiens identified by UniProt accession Q9H2L5, 321 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9H2L5; gene symbol RASSF4.
- Organism: Homo sapiens.
- Length: 321 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, protein measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras association domain-containing protein 4 |
|---|---|
| UniProt accession | Q9H2L5 |
| Gene | RASSF4 |
| Organism | Homo sapiens |
| Length | 321 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.30
- protein measurement · score 0.28
- mean corpuscular volume · score 0.15
- mean reticulocyte volume · score 0.13
- erythrocyte count · score 0.13
- mean corpuscular hemoglobin concentration · score 0.12
- Immature Reticulocyte Fraction Measurement · score 0.11
- diastolic blood pressure · score 0.10
- heel bone mineral density · score 0.08
- red blood cell density measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2L5-F1 | alphafold | PREDICTED | 77.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2L5.
Amino-acid sequence (321 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RASSF4?
The strongest Open Targets associations for RASSF4 are Red cell distribution width, protein measurement, mean corpuscular volume, mean reticulocyte volume and erythrocyte count.
How long is the RASSF4 protein?
The Homo sapiens RASSF4 protein (UniProt Q9H2L5) is 321 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2L5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2L5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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