Kallikrein-15 (KLK15)
Homo sapiens — UniProt Q9H2R5
Data last refreshed: (UniProt release unknown)
Key facts
Kallikrein-15 (KLK15) is a protein from Homo sapiens identified by UniProt accession Q9H2R5, 256 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9H2R5; gene symbol KLK15.
- Organism: Homo sapiens.
- Length: 256 amino acids.
- Top disease associations (Open Targets): prostate carcinoma, cystatin C measurement and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kallikrein-15 |
|---|---|
| UniProt accession | Q9H2R5 |
| Gene | KLK15 |
| Organism | Homo sapiens |
| Length | 256 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.19
- cystatin C measurement · score 0.05
- neoplasm · score 0.02
- benign prostatic hyperplasia · score 0.02
- carcinoma of liver and intrahepatic biliary tract · score 0.02
- Crohn's disease · score 0.02
- infect · score 0.02
- infection · score 0.02
- colorectal adenocarcinoma · score 0.01
- pachyonychia congenita · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2R5-F1 | alphafold | PREDICTED | 85.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2R5.
Amino-acid sequence (256 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLK15?
The strongest Open Targets associations for KLK15 are prostate carcinoma, cystatin C measurement, neoplasm, benign prostatic hyperplasia and carcinoma of liver and intrahepatic biliary tract.
How long is the KLK15 protein?
The Homo sapiens KLK15 protein (UniProt Q9H2R5) is 256 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2R5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2R5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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