Tenomodulin (TNMD)
Homo sapiens — UniProt Q9H2S6
Data last refreshed: (UniProt release unknown)
Key facts
Tenomodulin (TNMD) is a protein from Homo sapiens identified by UniProt accession Q9H2S6, 317 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q9H2S6; gene symbol TNMD.
- Organism: Homo sapiens.
- Length: 317 amino acids.
- Top disease associations (Open Targets): Arthrogryposis - hyperkeratosis, lethal form, arthrogryposis-hyperkeratosis syndrome, lethal form and carpal tunnel syndrome 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tenomodulin |
|---|---|
| UniProt accession | Q9H2S6 |
| Gene | TNMD |
| Organism | Homo sapiens |
| Length | 317 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- Arthrogryposis - hyperkeratosis, lethal form · score 0.07
- arthrogryposis-hyperkeratosis syndrome, lethal form · score 0.07
- carpal tunnel syndrome 1 · score 0.05
- atrial fibrillation · score 0.03
- Obesity · score 0.02
- diabetes mellitus · score 0.02
- psoriasis · score 0.02
- age-related macular degeneration · score 0.01
- cryopyrin-associated periodic syndrome · score 0.01
- oral squamous cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2S6-F1 | alphafold | PREDICTED | 68.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2S6.
Amino-acid sequence (317 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TNMD?
The strongest Open Targets associations for TNMD are Arthrogryposis - hyperkeratosis, lethal form, arthrogryposis-hyperkeratosis syndrome, lethal form, carpal tunnel syndrome 1, atrial fibrillation and Obesity.
How long is the TNMD protein?
The Homo sapiens TNMD protein (UniProt Q9H2S6) is 317 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2S6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2S6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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