Homeobox protein MIXL1 (MIXL1)
Homo sapiens — UniProt Q9H2W2
Data last refreshed: (UniProt release unknown)
Key facts
Homeobox protein MIXL1 (MIXL1) is a protein from Homo sapiens identified by UniProt accession Q9H2W2, 232 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q9H2W2; gene symbol MIXL1.
- Organism: Homo sapiens.
- Length: 232 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, sex hormone-binding globulin measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Homeobox protein MIXL1 |
|---|---|
| UniProt accession | Q9H2W2 |
| Gene | MIXL1 |
| Organism | Homo sapiens |
| Length | 232 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- sex hormone-binding globulin measurement · score 0.28
- mean platelet volume · score 0.26
- Red cell distribution width · score 0.19
- myeloid white cell count · score 0.13
- mean corpuscular volume · score 0.13
- mean corpuscular hemoglobin concentration · score 0.11
- acute myeloid leukemia · score 0.08
- neutrophil count · score 0.07
- mean corpuscular hemoglobin · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2W2-F1 | alphafold | PREDICTED | 65.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2W2.
Amino-acid sequence (232 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIXL1?
The strongest Open Targets associations for MIXL1 are neurodegenerative disease, sex hormone-binding globulin measurement, mean platelet volume, Red cell distribution width and myeloid white cell count.
How long is the MIXL1 protein?
The Homo sapiens MIXL1 protein (UniProt Q9H2W2) is 232 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2W2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2W2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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