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Chordin (CHRD)

Homo sapiens — UniProt Q9H2X0

Gene: CHRDHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Chordin (CHRD) is a protein from Homo sapiens identified by UniProt accession Q9H2X0, 955 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.

  • UniProt accession: Q9H2X0; gene symbol CHRD.
  • Organism: Homo sapiens.
  • Length: 955 amino acids.
  • Top disease associations (Open Targets): platelet count, platelet crit and total blood protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameChordin
UniProt accessionQ9H2X0
GeneCHRD
OrganismHomo sapiens
Length955 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (90)

Diseases linked to this target (Open Targets).

  • platelet count · score 0.20
  • platelet crit · score 0.18
  • total blood protein measurement · score 0.16
  • insomnia · score 0.16
  • sex hormone-binding globulin measurement · score 0.14
  • platelet-to-lymphocyte ratio · score 0.10
  • neutrophil count · score 0.08
  • mean corpuscular volume · score 0.07
  • monocyte percentage of leukocytes · score 0.05
  • auriculocondylar syndrome · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H2X0-F1alphafoldPREDICTED73.49—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2X0.

Amino-acid sequence (955 residues)

MPSLPAPPAP LLLLGLLLLG SRPARGAGPE PPVLPIRSEK EPLPVRGAAG CTFGGKVYAL DETWHPDLGE PFGVMRCVLC ACEAPQWGRR TRGPGRVSCK NIKPECPTPA CGQPRQLPGH CCQTCPQERS SSERQPSGLS FEYPRDPEHR SYSDRGEPGA EERARGDGHT DFVALLTGPR SQAVARARVS LLRSSLRFSI SYRRLDRPTR IRFSDSNGSV LFEHPAAPTQ DGLVCGVWRA VPRLSLRLLR AEQLHVALVT LTHPSGEVWG PLIRHRALAA ETFSAILTLE GPPQQGVGGI TLLTLSDTED SLHFLLLFRG LLEPRSGGLT QVPLRLQILH QGQLLRELQA NVSAQEPGFA EVLPNLTVQE MDWLVLGELQ MALEWAGRPG LRISGHIAAR KSCDVLQSVL CGADALIPVQ TGAAGSASLT LLGNGSLIYQ VQVVGTSSEV VAMTLETKPQ RRDQRTVLCH MAGLQPGGHT AVGICPGLGA RGAHMLLQNE LFLNVGTKDF PDGELRGHVA ALPYCGHSAR HDTLPVPLAG ALVLPPVKSQ AAGHAWLSLD THCHLHYEVL LAGLGGSEQG TVTAHLLGPP GTPGPRRLLK GFYGSEAQGV VKDLEPELLR HLAKGMASLM ITTKGSPRGE LRGQVHIANQ CEVGGLRLEA AGAEGVRALG APDTASAAPP VVPGLPALAP AKPGGPGRPR DPNTCFFEGQ QRPHGARWAP NYDPLCSLCT CQRRTVICDP VVCPPPSCPH PVQAPDQCCP VCPEKQDVRD LPGLPRSRDP GEGCYFDGDR SWRAAGTRWH PVVPPFGLIK CAVCTCKGGT GEVHCEKVQC PRLACAQPVR VNPTDCCKQC PVGSGAHPQL GDPMQADGPR GCRFAGQWFP ESQSWHPSVP PFGEMSCITC RCGAGVPHCE RDDCSLPLSC GSGKESRCCS RCTAHRRPAP ETRTDPELEK EAEGS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CHRD?

The strongest Open Targets associations for CHRD are platelet count, platelet crit, total blood protein measurement, insomnia and sex hormone-binding globulin measurement.

How long is the CHRD protein?

The Homo sapiens CHRD protein (UniProt Q9H2X0) is 955 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H2X0
GeneCHRD
OrganismHomo sapiens
Length955
Binders0
Diseases90
View on UniProt