C-type lectin domain family 4 member M (CLEC4M)
Homo sapiens — UniProt Q9H2X3
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 4 member M (CLEC4M) is a protein from Homo sapiens identified by UniProt accession Q9H2X3, 399 residues long. MolForge cross-references it against 0 known binders and 257 disease associations.
- UniProt accession: Q9H2X3; gene symbol CLEC4M.
- Organism: Homo sapiens.
- Length: 399 amino acids.
- Top disease associations (Open Targets): neutrophil count, leukocyte count and aspartate aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 4 member M |
|---|---|
| UniProt accession | Q9H2X3 |
| Gene | CLEC4M |
| Organism | Homo sapiens |
| Length | 399 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (257)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.39
- leukocyte count · score 0.37
- aspartate aminotransferase measurement · score 0.34
- myeloid white cell count · score 0.33
- von Willebrand factor measurement · score 0.31
- neutrophil percentage of leukocytes · score 0.30
- monocyte count · score 0.29
- lipoprotein A measurement · score 0.25
- IGF-1 measurement · score 0.25
- lymphocyte percentage of leukocytes · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2X3-F1 | alphafold | PREDICTED | 70.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2X3.
Amino-acid sequence (399 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC4M?
The strongest Open Targets associations for CLEC4M are neutrophil count, leukocyte count, aspartate aminotransferase measurement, myeloid white cell count and von Willebrand factor measurement.
How long is the CLEC4M protein?
The Homo sapiens CLEC4M protein (UniProt Q9H2X3) is 399 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2X3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2X3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.