Zinc finger protein 106 (ZNF106)

Homo sapiens — UniProt Q9H2Y7

Gene: ZNF106Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Zinc finger protein 106 (ZNF106) is a protein from Homo sapiens identified by UniProt accession Q9H2Y7, 1883 residues long. MolForge cross-references it against 0 known binders and 268 disease associations.

UniProt accession: Q9H2Y7; gene symbol ZNF106.
Organism: Homo sapiens.
Length: 1883 amino acids.
Top disease associations (Open Targets): red blood cell density measurement, erythrocyte count and sex hormone-binding globulin measurement.
3D structure: AlphaFold model available.

Target properties

Protein name	Zinc finger protein 106
UniProt accession	Q9H2Y7
Gene	ZNF106
Organism	Homo sapiens
Length	1883 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (268)

Diseases linked to this target (Open Targets).

red blood cell density measurement · score 0.35
erythrocyte count · score 0.32
sex hormone-binding globulin measurement · score 0.26
triglyceride measurement · score 0.13
high density lipoprotein cholesterol measurement · score 0.13
hemoglobin measurement · score 0.12
alcohol consumption measurement · score 0.12
alcohol drinking · score 0.12
C-reactive protein measurement · score 0.09
basophil count · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H2Y7-F1	alphafold	PREDICTED	44.57	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2Y7.

Amino-acid sequence (1883 residues)

MPVGRIECPS SPSFPRDISH ECRVCGVTEV GLSAYAKHIS GQLHKDNVDA QEREDDGKGE EEEEDYFDKE LIQLIKQRKE QSRQDEPSNS NQEINSDDRR PQWRREDRIP YQDRESYSQP AWHHRGPPQR DWKWEKDGFN NTRKNSFPHS LRNGGGPRGR SGWHKGVAGG SSTWFHNHSN SGGGWLSNSG AVDWNHNGTG RNSSWLSEGT GGFSSWHMNN SNGNWKSSVR STNNWNYSGP GDKFQPGRNR NSNCQMEDMT MLWNKKSNKS NKYSHDRYNW QRQENDKLGT VATYRGPSEG FTSDKFPSEG LLDFNFEQLE SQTTKQADTA TSKVSGKNGS AAREKPRRWT PYPSQKTLDL QSGLKDITGN KSEMIEKPLF DFSLITTGIQ EPQTDETRNS PTQKTQKEIH TGSLNHKASS DSAASFEVVR QCPTAEKPEQ EHTPNKMPSL KSPLLPCPAT KSLSQKQDPK NISKNTKTNF FSPGEHSNPS NKPTVEDNHG PYISKLRSSC PHVLKGNKST FGSQKQSGDN LNDTLRKAKE VLQCHESLQN PLLSTSKSTR NYAKASRNVE ESEKGSLKIE FQVHALEDES DGETSDTEKH GTKIGTLGSA TTELLSGSTR TADEKEEDDR ILKTSRELST SPCNPIVRQK ESELQMTSAA SPHPGLLLDL KTSLEDAQVD DSIKSHVSYE TEGFESASLD AELQKSDISQ PSGPLLPELS KLGFPASLQR DLTRHISLKS KTGVHLPEPN LNSARRIRNI SGHRKSETEK ESGLKPTLRQ ILNASRRNVN WEQVIQQVTK KKQELGKGLP RFGIEMVPLV QNEQEALDLD GEPDLSSLEG FQWEGVSISS SPGLARKRSL SESSVIMDRA PSVYSFFSEE GTGKENEPQQ MVSPSNSLRA GQSQKATMHL KQEVTPRAAS LRTGERAENV ATQRRHSAQL SSDHIIPLMH LAKDLNSQER SIPPSENQNS QESNGEGNCL SSSASSALAI SSLADAATDS SCTSGAEQND GQSIRKKRRA TGDGSSPELP SLERKNKRRK IKGKKERSQV DQLLNISLRE EELSKSLQCM DNNLLQARAA LQTAYVEVQR LLMLKQQITM EMSALRTHRI QILQGLQETY EPSEHPDQVP CSLTRERRNS RSQTSIDAAL LPTPFFPLFL EPPSSHVSPS PTGASLQITT SPTFQTHGSV PAPDSSVQIK QEPMSPEQDE NVNAVPPSSA CNVSKELLEA NREISDSCPV YPVITARLSL PESTESFHEP SQELKFSVEQ RNTRNRENSP SSQSAGLSSI NKEGEEPTKG NSGSEACTSS FLRLSFASET PLEKEPHSPA DQPEQQAEST LTSAETRGSK KKKKLRKKKS LRAAHVPENS DTEQDVLTVK PVRKVKAGKL IKGGKVTTST WEDSRTGREQ ESVRDEPDSD SSLEVLEIPN PQLEVVAIDS SESGEEKPDS PSKKDIWNST EQNPLETSRS GCDEVSSTSE IGTRYKDGIP VSVAETQTVI SSIKGSKNSS EISSEPGDDD EPTEGSFEGH QAAVNAIQIF GNLLYTCSAD KTVRVYNLVS RKCIGVFEGH TSKVNCLLVT QTSGKNAALY TGSSDHTIRC YNVKSRECVE QLQLEDRVLC LHSRWRILYA GLANGTVVTF NIKNNKRLEI FECHGPRAVS CLATAQEGAR KLLVVGSYDC TISVRDARNG LLLRTLEGHS KTILCMKVVN DLVFSGSSDQ SVHAHNIHTG ELVRIYKGHN HAVTVVNILG KVMVTACLDK FVRVYELQSH DRLQVYGGHK DMIMCMTIHK SMIYTGCYDG SIQAVRLNLM QNYRCWWHGC SLIFGVVDHL KQHLLTDHTN PNFQTLKCRW KNCDAFFTAR KGSKQDAAGH IERHAEDDSK IDS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF106?

The strongest Open Targets associations for ZNF106 are red blood cell density measurement, erythrocyte count, sex hormone-binding globulin measurement, triglyceride measurement and high density lipoprotein cholesterol measurement.

How long is the ZNF106 protein?

The Homo sapiens ZNF106 protein (UniProt Q9H2Y7) is 1883 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q9H2Y7 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q9H2Y7 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

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