Solute carrier organic anion transporter family member 5A1 (SLCO5A1)
Homo sapiens — UniProt Q9H2Y9
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier organic anion transporter family member 5A1 (SLCO5A1) is a protein from Homo sapiens identified by UniProt accession Q9H2Y9, 848 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q9H2Y9; gene symbol SLCO5A1.
- Organism: Homo sapiens.
- Length: 848 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): basophil count, leukocyte count and sphingolipid measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier organic anion transporter family member 5A1 |
|---|---|
| UniProt accession | Q9H2Y9 |
| Gene | SLCO5A1 |
| Organism | Homo sapiens |
| Length | 848 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- basophil count · score 0.38
- leukocyte count · score 0.35
- sphingolipid measurement · score 0.31
- neutrophil percentage of leukocytes · score 0.29
- neutrophil count · score 0.28
- basophil percentage of leukocytes · score 0.27
- visual perception measurement · score 0.21
- lymphocyte percentage of leukocytes · score 0.20
- metabolite measurement · score 0.13
- fibroblastic disorder · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2Y9-F1 | alphafold | PREDICTED | 70.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2Y9.
Amino-acid sequence (848 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLCO5A1?
The strongest Open Targets associations for SLCO5A1 are basophil count, leukocyte count, sphingolipid measurement, neutrophil percentage of leukocytes and neutrophil count.
How long is the SLCO5A1 protein?
The Homo sapiens SLCO5A1 protein (UniProt Q9H2Y9) is 848 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2Y9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2Y9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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