Matrix metalloproteinase-27 (MMP27)
Homo sapiens — UniProt Q9H306
Data last refreshed: (UniProt release unknown)
Key facts
Matrix metalloproteinase-27 (MMP27) is a protein from Homo sapiens identified by UniProt accession Q9H306, 513 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9H306; gene symbol MMP27.
- Organism: Homo sapiens.
- Length: 513 amino acids.
- Top disease associations (Open Targets): blood protein measurement, matrix metalloproteinase measurement and matrix metalloproteinase 10 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Matrix metalloproteinase-27 |
|---|---|
| UniProt accession | Q9H306 |
| Gene | MMP27 |
| Organism | Homo sapiens |
| Length | 513 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.30
- matrix metalloproteinase measurement · score 0.28
- matrix metalloproteinase 10 measurement · score 0.27
- protein measurement · score 0.23
- neurodegenerative disease · score 0.15
- Posterior Leukoencephalopathy Syndrome · score 0.05
- neoplasm · score 0.04
- oral squamous cell carcinoma · score 0.04
- reticulocyte count · score 0.04
- matrix metalloproteinase 1 measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H306-F1 | alphafold | PREDICTED | 80.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H306.
Amino-acid sequence (513 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MMP27?
The strongest Open Targets associations for MMP27 are blood protein measurement, matrix metalloproteinase measurement, matrix metalloproteinase 10 measurement, protein measurement and neurodegenerative disease.
How long is the MMP27 protein?
The Homo sapiens MMP27 protein (UniProt Q9H306) is 513 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H306 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H306 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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