Pinin (PNN)
Homo sapiens — UniProt Q9H307
Data last refreshed: (UniProt release unknown)
Key facts
Pinin (PNN) is a protein from Homo sapiens identified by UniProt accession Q9H307, 717 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.
- UniProt accession: Q9H307; gene symbol PNN.
- Organism: Homo sapiens.
- Length: 717 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, vitamin D measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pinin |
|---|---|
| UniProt accession | Q9H307 |
| Gene | PNN |
| Organism | Homo sapiens |
| Length | 717 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (111)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- vitamin D measurement · score 0.17
- self reported educational attainment · score 0.13
- neoplasm · score 0.09
- hepatocellular carcinoma · score 0.08
- blood pressure · score 0.08
- renal cell carcinoma · score 0.08
- lymphocyte count · score 0.07
- cancer · score 0.04
- platelet component distribution width · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H307-F1 | alphafold | PREDICTED | 57.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H307.
Amino-acid sequence (717 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PNN?
The strongest Open Targets associations for PNN are neurodegenerative disease, vitamin D measurement, self reported educational attainment, neoplasm and hepatocellular carcinoma.
How long is the PNN protein?
The Homo sapiens PNN protein (UniProt Q9H307) is 717 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H307 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H307 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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