Ammonium transporter Rh type B (RHBG)
Homo sapiens — UniProt Q9H310
Data last refreshed: (UniProt release unknown)
Key facts
Ammonium transporter Rh type B (RHBG) is a protein from Homo sapiens identified by UniProt accession Q9H310, 458 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q9H310; gene symbol RHBG.
- Organism: Homo sapiens.
- Length: 458 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): cutaneous melanoma, genetic disorder and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ammonium transporter Rh type B |
|---|---|
| UniProt accession | Q9H310 |
| Gene | RHBG |
| Organism | Homo sapiens |
| Length | 458 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.17
- genetic disorder · score 0.12
- body mass index · score 0.06
- isolated asymptomatic elevation of creatine phosphokinase · score 0.06
- non-small cell lung carcinoma · score 0.05
- hemochromatosis type 5 · score 0.05
- FTH1-related iron overload · score 0.05
- pentosuria · score 0.04
- Liddle syndrome 2 · score 0.04
- hepatocellular carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H310-F1 | alphafold | PREDICTED | 93.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H310.
Amino-acid sequence (458 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RHBG?
The strongest Open Targets associations for RHBG are cutaneous melanoma, genetic disorder, body mass index, isolated asymptomatic elevation of creatine phosphokinase and non-small cell lung carcinoma.
How long is the RHBG protein?
The Homo sapiens RHBG protein (UniProt Q9H310) is 458 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H310 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H310 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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