Protein tweety homolog 1 (TTYH1)
Homo sapiens — UniProt Q9H313
Data last refreshed: (UniProt release unknown)
Key facts
Protein tweety homolog 1 (TTYH1) is a protein from Homo sapiens identified by UniProt accession Q9H313, 450 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q9H313; gene symbol TTYH1.
- Organism: Homo sapiens.
- Length: 450 amino acids.
- Top disease associations (Open Targets): idiopathic pulmonary fibrosis, lymphocyte count and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein tweety homolog 1 |
|---|---|
| UniProt accession | Q9H313 |
| Gene | TTYH1 |
| Organism | Homo sapiens |
| Length | 450 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- idiopathic pulmonary fibrosis · score 0.23
- lymphocyte count · score 0.18
- glioblastoma multiforme · score 0.18
- breast adenocarcinoma · score 0.16
- head and neck squamous cell carcinoma · score 0.12
- self reported educational attainment · score 0.11
- drug use measurement · score 0.06
- cancer · score 0.04
- breast carcinoma · score 0.04
- medulloblastoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H313-F1 | alphafold | PREDICTED | 89.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H313.
Amino-acid sequence (450 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTYH1?
The strongest Open Targets associations for TTYH1 are idiopathic pulmonary fibrosis, lymphocyte count, glioblastoma multiforme, breast adenocarcinoma and head and neck squamous cell carcinoma.
How long is the TTYH1 protein?
The Homo sapiens TTYH1 protein (UniProt Q9H313) is 450 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H313 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H313 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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