Variable charge X-linked protein 1 (VCX)
Homo sapiens — UniProt Q9H320
Data last refreshed: (UniProt release unknown)
Key facts
Variable charge X-linked protein 1 (VCX) is a protein from Homo sapiens identified by UniProt accession Q9H320, 206 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q9H320; gene symbol VCX.
- Organism: Homo sapiens.
- Length: 206 amino acids.
- Top disease associations (Open Targets): neoplasm, cancer and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Variable charge X-linked protein 1 |
|---|---|
| UniProt accession | Q9H320 |
| Gene | VCX |
| Organism | Homo sapiens |
| Length | 206 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.02
- cancer · score 0.02
- hepatocellular carcinoma · score 0.02
- melanoma · score 0.02
- chronic hepatitis B virus infection · score 0.01
- breast cancer · score 0.01
- major depressive disorder · score 0.01
- squamous cell carcinoma · score 0.01
- triple-negative breast cancer · score 0.01
- recessive X-linked ichthyosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H320-F1 | alphafold | PREDICTED | 51.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H320.
Amino-acid sequence (206 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VCX?
The strongest Open Targets associations for VCX are neoplasm, cancer, hepatocellular carcinoma, melanoma and chronic hepatitis B virus infection.
How long is the VCX protein?
The Homo sapiens VCX protein (UniProt Q9H320) is 206 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H320 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H320 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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