Variable charge X-linked protein 2 (VCX2)
Homo sapiens — UniProt Q9H322
Data last refreshed: (UniProt release unknown)
Key facts
Variable charge X-linked protein 2 (VCX2) is a protein from Homo sapiens identified by UniProt accession Q9H322, 139 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q9H322; gene symbol VCX2.
- Organism: Homo sapiens.
- Length: 139 amino acids.
- Top disease associations (Open Targets): melanoma, cancer and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Variable charge X-linked protein 2 |
|---|---|
| UniProt accession | Q9H322 |
| Gene | VCX2 |
| Organism | Homo sapiens |
| Length | 139 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- melanoma · score 0.06
- cancer · score 0.06
- neoplasm · score 0.04
- triple-negative breast cancer · score 0.01
- recessive X-linked ichthyosis · score 0.01
- urinary bladder carcinoma · score 0.00
- metastatic melanoma · score 0.00
- breast cancer · score 0.00
- partial epilepsy · score 0.00
- ichthyosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H322-F1 | alphafold | PREDICTED | 62.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H322.
Amino-acid sequence (139 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VCX2?
The strongest Open Targets associations for VCX2 are melanoma, cancer, neoplasm, triple-negative breast cancer and recessive X-linked ichthyosis.
How long is the VCX2 protein?
The Homo sapiens VCX2 protein (UniProt Q9H322) is 139 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H322 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H322 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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