Band 4.1-like protein 4B (EPB41L4B)
Homo sapiens — UniProt Q9H329
Data last refreshed: (UniProt release unknown)
Key facts
Band 4.1-like protein 4B (EPB41L4B) is a protein from Homo sapiens identified by UniProt accession Q9H329, 900 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.
- UniProt accession: Q9H329; gene symbol EPB41L4B.
- Organism: Homo sapiens.
- Length: 900 amino acids.
- Top disease associations (Open Targets): serum alanine aminotransferase measurement, neurodegenerative disease and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Band 4.1-like protein 4B |
|---|---|
| UniProt accession | Q9H329 |
| Gene | EPB41L4B |
| Organism | Homo sapiens |
| Length | 900 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- serum alanine aminotransferase measurement · score 0.47
- neurodegenerative disease · score 0.45
- serum gamma-glutamyl transferase measurement · score 0.40
- waist-hip ratio · score 0.30
- low density lipoprotein cholesterol measurement · score 0.26
- BMI-adjusted waist-hip ratio · score 0.25
- hemoglobin measurement · score 0.24
- body mass index · score 0.24
- type 2 diabetes mellitus · score 0.23
- lean body mass · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H329-F1 | alphafold | PREDICTED | 58.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H329.
Amino-acid sequence (900 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EPB41L4B?
The strongest Open Targets associations for EPB41L4B are serum alanine aminotransferase measurement, neurodegenerative disease, serum gamma-glutamyl transferase measurement, waist-hip ratio and low density lipoprotein cholesterol measurement.
How long is the EPB41L4B protein?
The Homo sapiens EPB41L4B protein (UniProt Q9H329) is 900 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H329 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H329 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.