Transmembrane protein 245 (TMEM245)
Homo sapiens — UniProt Q9H330
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 245 (TMEM245) is a protein from Homo sapiens identified by UniProt accession Q9H330, 879 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9H330; gene symbol TMEM245.
- Organism: Homo sapiens.
- Length: 879 amino acids.
- Top disease associations (Open Targets): cognitive function measurement, self reported educational attainment and age at menarche.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 245 |
|---|---|
| UniProt accession | Q9H330 |
| Gene | TMEM245 |
| Organism | Homo sapiens |
| Length | 879 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- cognitive function measurement · score 0.41
- self reported educational attainment · score 0.37
- age at menarche · score 0.36
- electrocardiography · score 0.32
- body height · score 0.29
- mathematical ability · score 0.29
- gut microbiome measurement · score 0.20
- lean body mass · score 0.14
- waist-hip ratio · score 0.13
- fat body mass · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H330-F1 | alphafold | PREDICTED | 68.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H330.
Amino-acid sequence (879 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM245?
The strongest Open Targets associations for TMEM245 are cognitive function measurement, self reported educational attainment, age at menarche, electrocardiography and body height.
How long is the TMEM245 protein?
The Homo sapiens TMEM245 protein (UniProt Q9H330) is 879 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H330 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H330 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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