Forkhead box protein P1 (FOXP1)
Homo sapiens — UniProt Q9H334
Data last refreshed: (UniProt release unknown)
Key facts
Forkhead box protein P1 (FOXP1) is a protein from Homo sapiens identified by UniProt accession Q9H334, 677 residues long. MolForge cross-references it against 0 known binders and 731 disease associations.
- UniProt accession: Q9H334; gene symbol FOXP1.
- Organism: Homo sapiens.
- Length: 677 amino acids.
- Top disease associations (Open Targets): intellectual disability-severe speech delay-mild dysmorphism syndrome, intellectual disability with language impairment and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Forkhead box protein P1 |
|---|---|
| UniProt accession | Q9H334 |
| Gene | FOXP1 |
| Organism | Homo sapiens |
| Length | 677 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (731)
Diseases linked to this target (Open Targets).
- intellectual disability-severe speech delay-mild dysmorphism syndrome · score 0.79
- intellectual disability with language impairment · score 0.73
- genetic disorder · score 0.54
- Intellectual disability · score 0.52
- lymphocyte count · score 0.48
- self reported educational attainment · score 0.48
- neutrophil count · score 0.47
- intelligence · score 0.46
- body height · score 0.46
- risk-taking behaviour · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H334-F1 | alphafold | PREDICTED | 57.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H334.
Amino-acid sequence (677 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FOXP1?
The strongest Open Targets associations for FOXP1 are intellectual disability-severe speech delay-mild dysmorphism syndrome, intellectual disability with language impairment, genetic disorder, Intellectual disability and lymphocyte count.
How long is the FOXP1 protein?
The Homo sapiens FOXP1 protein (UniProt Q9H334) is 677 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H334 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H334 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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