Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1)
Homo sapiens — UniProt Q9H336
Data last refreshed: (UniProt release unknown)
Key facts
Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) is a protein from Homo sapiens identified by UniProt accession Q9H336, 500 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q9H336; gene symbol CRISPLD1.
- Organism: Homo sapiens.
- Length: 500 amino acids.
- Top disease associations (Open Targets): body height, BMI-adjusted waist circumference and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cysteine-rich secretory protein LCCL domain-containing 1 |
|---|---|
| UniProt accession | Q9H336 |
| Gene | CRISPLD1 |
| Organism | Homo sapiens |
| Length | 500 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- body height · score 0.67
- BMI-adjusted waist circumference · score 0.39
- appendicular lean mass · score 0.38
- BMI-adjusted hip circumference · score 0.38
- forced expiratory volume · score 0.36
- sitting height measurement · score 0.33
- pulse pressure measurement · score 0.28
- optic cup area measurement · score 0.26
- breast carcinoma · score 0.03
- astrocytoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H336-F1 | alphafold | PREDICTED | 80.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H336.
Amino-acid sequence (500 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CRISPLD1?
The strongest Open Targets associations for CRISPLD1 are body height, BMI-adjusted waist circumference, appendicular lean mass, BMI-adjusted hip circumference and forced expiratory volume.
How long is the CRISPLD1 protein?
The Homo sapiens CRISPLD1 protein (UniProt Q9H336) is 500 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H336 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H336 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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