Ubiquilin-3 (UBQLN3)
Homo sapiens — UniProt Q9H347
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquilin-3 (UBQLN3) is a protein from Homo sapiens identified by UniProt accession Q9H347, 655 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q9H347; gene symbol UBQLN3.
- Organism: Homo sapiens.
- Length: 655 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, sensory perception of smell and COVID-19.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquilin-3 |
|---|---|
| UniProt accession | Q9H347 |
| Gene | UBQLN3 |
| Organism | Homo sapiens |
| Length | 655 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- sensory perception of smell · score 0.02
- COVID-19 · score 0.01
- cancer · score 0.01
- complete androgen insensitivity syndrome · score 0.01
- hepatocellular carcinoma · score 0.00
- Infertility · score 0.00
- papillary thyroid carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H347-F1 | alphafold | PREDICTED | 55.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H347.
Amino-acid sequence (655 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBQLN3?
The strongest Open Targets associations for UBQLN3 are neurodegenerative disease, sensory perception of smell, COVID-19, cancer and complete androgen insensitivity syndrome.
How long is the UBQLN3 protein?
The Homo sapiens UBQLN3 protein (UniProt Q9H347) is 655 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H347 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H347 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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