Polyadenylate-binding protein 3 (PABPC3)
Homo sapiens — UniProt Q9H361
Data last refreshed: (UniProt release unknown)
Key facts
Polyadenylate-binding protein 3 (PABPC3) is a protein from Homo sapiens identified by UniProt accession Q9H361, 631 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9H361; gene symbol PABPC3.
- Organism: Homo sapiens.
- Length: 631 amino acids.
- Top disease associations (Open Targets): proline measurement, Abnormal sperm morphology and lung adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polyadenylate-binding protein 3 |
|---|---|
| UniProt accession | Q9H361 |
| Gene | PABPC3 |
| Organism | Homo sapiens |
| Length | 631 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- proline measurement · score 0.03
- Abnormal sperm morphology · score 0.02
- lung adenocarcinoma · score 0.01
- cancer · score 0.01
- breast cancer · score 0.01
- neoplasm · score 0.01
- transitional cell carcinoma of kidney · score 0.01
- Infertility · score 0.01
- Azoospermia · score 0.01
- gonorrhea · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H361-F1 | alphafold | PREDICTED | 76.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H361.
Amino-acid sequence (631 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PABPC3?
The strongest Open Targets associations for PABPC3 are proline measurement, Abnormal sperm morphology, lung adenocarcinoma, cancer and breast cancer.
How long is the PABPC3 protein?
The Homo sapiens PABPC3 protein (UniProt Q9H361) is 631 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H361 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H361 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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