Gametogenetin-binding protein 2 (GGNBP2)
Homo sapiens — UniProt Q9H3C7
Data last refreshed: (UniProt release unknown)
Key facts
Gametogenetin-binding protein 2 (GGNBP2) is a protein from Homo sapiens identified by UniProt accession Q9H3C7, 697 residues long. MolForge cross-references it against 0 known binders and 235 disease associations.
- UniProt accession: Q9H3C7; gene symbol GGNBP2.
- Organism: Homo sapiens.
- Length: 697 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, macrophage inflammatory protein 1b measurement and CCL4 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Gametogenetin-binding protein 2 |
|---|---|
| UniProt accession | Q9H3C7 |
| Gene | GGNBP2 |
| Organism | Homo sapiens |
| Length | 697 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (235)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- macrophage inflammatory protein 1b measurement · score 0.20
- CCL4 measurement · score 0.20
- body fat percentage · score 0.18
- body mass index · score 0.18
- fat body mass · score 0.16
- self reported educational attainment · score 0.16
- lean body mass · score 0.16
- glomerular filtration rate · score 0.14
- intelligence · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3C7-F1 | alphafold | PREDICTED | 68.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3C7.
Amino-acid sequence (697 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GGNBP2?
The strongest Open Targets associations for GGNBP2 are neurodegenerative disease, macrophage inflammatory protein 1b measurement, CCL4 measurement, body fat percentage and body mass index.
How long is the GGNBP2 protein?
The Homo sapiens GGNBP2 protein (UniProt Q9H3C7) is 697 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3C7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3C7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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