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Probable serine carboxypeptidase CPVL (CPVL)

Homo sapiens — UniProt Q9H3G5

Gene: CPVLHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Probable serine carboxypeptidase CPVL (CPVL) is a protein from Homo sapiens identified by UniProt accession Q9H3G5, 476 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.

  • UniProt accession: Q9H3G5; gene symbol CPVL.
  • Organism: Homo sapiens.
  • Length: 476 amino acids.
  • Top disease associations (Open Targets): non-melanoma skin carcinoma, skin cancer and basal cell carcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProbable serine carboxypeptidase CPVL
UniProt accessionQ9H3G5
GeneCPVL
OrganismHomo sapiens
Length476 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (78)

Diseases linked to this target (Open Targets).

  • non-melanoma skin carcinoma · score 0.39
  • skin cancer · score 0.38
  • basal cell carcinoma · score 0.34
  • cortical thickness · score 0.32
  • cortical surface area measurement · score 0.32
  • FEV/FVC ratio · score 0.31
  • skin carcinoma · score 0.28
  • Vitiligo · score 0.27
  • skin neoplasm · score 0.27
  • keratinocyte carcinoma · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H3G5-F1alphafoldPREDICTED93.18—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3G5.

Amino-acid sequence (476 residues)

MVGAMWKVIV SLVLLMPGPC DGLFRSLYRS VSMPPKGDSG QPLFLTPYIE AGKIQKGREL SLVGPFPGLN MKSYAGFLTV NKTYNSNLFF WFFPAQIQPE DAPVVLWLQG GPGGSSMFGL FVEHGPYVVT SNMTLRDRDF PWTTTLSMLY IDNPVGTGFS FTDDTHGYAV NEDDVARDLY SALIQFFQIF PEYKNNDFYV TGESYAGKYV PAIAHLIHSL NPVREVKINL NGIAIGDGYS DPESIIGGYA EFLYQIGLLD EKQKKYFQKQ CHECIEHIRK QNWFEAFEIL DKLLDGDLTS DPSYFQNVTG CSNYYNFLRC TEPEDQLYYV KFLSLPEVRQ AIHVGNQTFN DGTIVEKYLR EDTVQSVKPW LTEIMNNYKV LIYNGQLDII VAAALTERSL MGMDWKGSQE YKKAEKKVWK IFKSDSEVAG YIRQAGDFHQ VIIRGGGHIL PYDQPLRAFD MINRFIYGKG WDPYVG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CPVL?

The strongest Open Targets associations for CPVL are non-melanoma skin carcinoma, skin cancer, basal cell carcinoma, cortical thickness and cortical surface area measurement.

How long is the CPVL protein?

The Homo sapiens CPVL protein (UniProt Q9H3G5) is 476 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H3G5
GeneCPVL
OrganismHomo sapiens
Length476
Binders0
Diseases78
View on UniProt