Transcription elongation factor A protein-like 2 (TCEAL2)
Homo sapiens — UniProt Q9H3H9
Data last refreshed: (UniProt release unknown)
Key facts
Transcription elongation factor A protein-like 2 (TCEAL2) is a protein from Homo sapiens identified by UniProt accession Q9H3H9, 227 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9H3H9; gene symbol TCEAL2.
- Organism: Homo sapiens.
- Length: 227 amino acids.
- Top disease associations (Open Targets): cancer, nonpapillary renal cell carcinoma and ovarian carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription elongation factor A protein-like 2 |
|---|---|
| UniProt accession | Q9H3H9 |
| Gene | TCEAL2 |
| Organism | Homo sapiens |
| Length | 227 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- cancer · score 0.08
- nonpapillary renal cell carcinoma · score 0.08
- ovarian carcinoma · score 0.05
- neoplasm · score 0.04
- breast carcinoma · score 0.03
- clear cell renal carcinoma · score 0.03
- colorectal adenocarcinoma · score 0.03
- large cell medulloblastoma · score 0.03
- papillary renal cell carcinoma · score 0.03
- colorectal cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3H9-F1 | alphafold | PREDICTED | 61.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3H9.
Amino-acid sequence (227 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TCEAL2?
The strongest Open Targets associations for TCEAL2 are cancer, nonpapillary renal cell carcinoma, ovarian carcinoma, neoplasm and breast carcinoma.
How long is the TCEAL2 protein?
The Homo sapiens TCEAL2 protein (UniProt Q9H3H9) is 227 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3H9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3H9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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