BolA-like protein 2 (BOLA2)
Homo sapiens — UniProt Q9H3K6
Data last refreshed: (UniProt release unknown)
Key facts
BolA-like protein 2 (BOLA2) is a protein from Homo sapiens identified by UniProt accession Q9H3K6, 86 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q9H3K6; gene symbol BOLA2.
- Organism: Homo sapiens.
- Length: 86 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, cancer and MODY.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BolA-like protein 2 |
|---|---|
| UniProt accession | Q9H3K6 |
| Gene | BOLA2 |
| Organism | Homo sapiens |
| Length | 86 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.07
- cancer · score 0.07
- MODY · score 0.06
- neoplasm · score 0.06
- hemoglobin D disease · score 0.05
- microcytic anemia with liver iron overload · score 0.05
- Adult-onset autosomal recessive sideroblastic anemia · score 0.05
- hemoglobin E-beta-thalassemia syndrome · score 0.04
- severe congenital hypochromic anemia with ringed sideroblasts · score 0.04
- FTH1-related iron overload · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3K6-F1 | alphafold | PREDICTED | 92.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3K6.
Amino-acid sequence (86 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BOLA2?
The strongest Open Targets associations for BOLA2 are hepatocellular carcinoma, cancer, MODY, neoplasm and hemoglobin D disease.
How long is the BOLA2 protein?
The Homo sapiens BOLA2 protein (UniProt Q9H3K6) is 86 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3K6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3K6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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