Ataxin-3-like protein (ATXN3L)
Homo sapiens — UniProt Q9H3M9
Data last refreshed: (UniProt release unknown)
Key facts
Ataxin-3-like protein (ATXN3L) is a protein from Homo sapiens identified by UniProt accession Q9H3M9, 355 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9H3M9; gene symbol ATXN3L.
- Organism: Homo sapiens.
- Length: 355 amino acids.
- Top disease associations (Open Targets): low grade glioma, ovarian cancer and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ataxin-3-like protein |
|---|---|
| UniProt accession | Q9H3M9 |
| Gene | ATXN3L |
| Organism | Homo sapiens |
| Length | 355 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- autoimmune disease · score 0.04
- Huntington disease · score 0.03
- pemphigus vulgaris · score 0.03
- amyotrophic lateral sclerosis type 15 · score 0.03
- familial amyotrophic lateral sclerosis · score 0.03
- progressive non-fluent aphasia · score 0.03
- lung carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3M9-F1 | alphafold | PREDICTED | 71.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3M9.
Amino-acid sequence (355 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATXN3L?
The strongest Open Targets associations for ATXN3L are low grade glioma, ovarian cancer, breast adenocarcinoma, autoimmune disease and Huntington disease.
How long is the ATXN3L protein?
The Homo sapiens ATXN3L protein (UniProt Q9H3M9) is 355 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.