Golgi resident protein GCP60 (ACBD3)
Homo sapiens — UniProt Q9H3P7
Data last refreshed: (UniProt release unknown)
Key facts
Golgi resident protein GCP60 (ACBD3) is a protein from Homo sapiens identified by UniProt accession Q9H3P7, 528 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9H3P7; gene symbol ACBD3.
- Organism: Homo sapiens.
- Length: 528 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, genetic disorder and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi resident protein GCP60 |
|---|---|
| UniProt accession | Q9H3P7 |
| Gene | ACBD3 |
| Organism | Homo sapiens |
| Length | 528 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.16
- genetic disorder · score 0.12
- cancer · score 0.09
- Red cell distribution width · score 0.08
- neoplasm · score 0.06
- sex hormone-binding globulin measurement · score 0.05
- Adult-onset autosomal recessive sideroblastic anemia · score 0.05
- neutrophil count · score 0.04
- dehydrated hereditary stomatocytosis · score 0.04
- hemoglobin D disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3P7-F1 | alphafold | PREDICTED | 78.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3P7.
Amino-acid sequence (528 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACBD3?
The strongest Open Targets associations for ACBD3 are alkaline phosphatase measurement, genetic disorder, cancer, Red cell distribution width and neoplasm.
How long is the ACBD3 protein?
The Homo sapiens ACBD3 protein (UniProt Q9H3P7) is 528 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3P7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3P7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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