Cdc42 effector protein 4 (CDC42EP4)
Homo sapiens — UniProt Q9H3Q1
Data last refreshed: (UniProt release unknown)
Key facts
Cdc42 effector protein 4 (CDC42EP4) is a protein from Homo sapiens identified by UniProt accession Q9H3Q1, 356 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H3Q1; gene symbol CDC42EP4.
- Organism: Homo sapiens.
- Length: 356 amino acids.
- Top disease associations (Open Targets): p-cresol sulfate measurement, white matter microstructure measurement and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cdc42 effector protein 4 |
|---|---|
| UniProt accession | Q9H3Q1 |
| Gene | CDC42EP4 |
| Organism | Homo sapiens |
| Length | 356 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- p-cresol sulfate measurement · score 0.11
- white matter microstructure measurement · score 0.08
- neutrophil count · score 0.03
- hypertrophic cardiomyopathy · score 0.02
- juvenile idiopathic arthritis · score 0.02
- Stroke · score 0.01
- Bartsocas-Papas syndrome 1 · score 0.01
- polycystic ovary syndrome · score 0.01
- psoriasis · score 0.01
- Alzheimer disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3Q1-F1 | alphafold | PREDICTED | 58.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3Q1.
Amino-acid sequence (356 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDC42EP4?
The strongest Open Targets associations for CDC42EP4 are p-cresol sulfate measurement, white matter microstructure measurement, neutrophil count, hypertrophic cardiomyopathy and juvenile idiopathic arthritis.
How long is the CDC42EP4 protein?
The Homo sapiens CDC42EP4 protein (UniProt Q9H3Q1) is 356 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3Q1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3Q1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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