Galactose-3-O-sulfotransferase 2 (GAL3ST2)
Homo sapiens — UniProt Q9H3Q3
Data last refreshed: (UniProt release unknown)
Key facts
Galactose-3-O-sulfotransferase 2 (GAL3ST2) is a protein from Homo sapiens identified by UniProt accession Q9H3Q3, 398 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9H3Q3; gene symbol GAL3ST2.
- Organism: Homo sapiens.
- Length: 398 amino acids.
- Top disease associations (Open Targets): cancer antigen 125 measurement, asthma and Crohn's disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Galactose-3-O-sulfotransferase 2 |
|---|---|
| UniProt accession | Q9H3Q3 |
| Gene | GAL3ST2 |
| Organism | Homo sapiens |
| Length | 398 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- cancer antigen 125 measurement · score 0.37
- asthma · score 0.26
- Crohn's disease · score 0.25
- blood protein measurement · score 0.25
- kallikrein-11 measurement · score 0.22
- ulcerative colitis · score 0.21
- respiratory tract infectious disorder · score 0.20
- ankylosing spondylitis · score 0.20
- sclerosing cholangitis · score 0.20
- psoriasis · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3Q3-F1 | alphafold | PREDICTED | 92.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3Q3.
Amino-acid sequence (398 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GAL3ST2?
The strongest Open Targets associations for GAL3ST2 are cancer antigen 125 measurement, asthma, Crohn's disease, blood protein measurement and kallikrein-11 measurement.
How long is the GAL3ST2 protein?
The Homo sapiens GAL3ST2 protein (UniProt Q9H3Q3) is 398 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3Q3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3Q3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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