Lysine-specific demethylase 4C (KDM4C)
Homo sapiens — UniProt Q9H3R0
Data last refreshed: (UniProt release unknown)
Key facts
Lysine-specific demethylase 4C (KDM4C) is a protein from Homo sapiens identified by UniProt accession Q9H3R0, 1056 residues long. MolForge cross-references it against 0 known binders and 178 disease associations.
- UniProt accession: Q9H3R0; gene symbol KDM4C.
- Organism: Homo sapiens.
- Length: 1056 amino acids.
- Top disease associations (Open Targets): age at menarche, body height and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysine-specific demethylase 4C |
|---|---|
| UniProt accession | Q9H3R0 |
| Gene | KDM4C |
| Organism | Homo sapiens |
| Length | 1056 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (178)
Diseases linked to this target (Open Targets).
- age at menarche · score 0.44
- body height · score 0.42
- mean corpuscular volume · score 0.41
- mathematical ability · score 0.36
- body mass index · score 0.36
- puberty onset measurement · score 0.31
- eosinophil count · score 0.31
- tea consumption measurement · score 0.30
- cognitive function measurement · score 0.30
- self reported educational attainment · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3R0-F1 | alphafold | PREDICTED | 71.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3R0.
Amino-acid sequence (1056 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KDM4C?
The strongest Open Targets associations for KDM4C are age at menarche, body height, mean corpuscular volume, mathematical ability and body mass index.
How long is the KDM4C protein?
The Homo sapiens KDM4C protein (UniProt Q9H3R0) is 1056 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3R0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3R0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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