Semaphorin-6C (SEMA6C)
Homo sapiens — UniProt Q9H3T2
Data last refreshed: (UniProt release unknown)
Key facts
Semaphorin-6C (SEMA6C) is a protein from Homo sapiens identified by UniProt accession Q9H3T2, 930 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9H3T2; gene symbol SEMA6C.
- Organism: Homo sapiens.
- Length: 930 amino acids.
- Top disease associations (Open Targets): body mass index, age at menarche and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Semaphorin-6C |
|---|---|
| UniProt accession | Q9H3T2 |
| Gene | SEMA6C |
| Organism | Homo sapiens |
| Length | 930 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- body mass index · score 0.10
- age at menarche · score 0.09
- cancer · score 0.08
- monocyte count · score 0.07
- osteoporosis · score 0.06
- pancreatic neoplasm · score 0.06
- body height · score 0.04
- skin carcinoma · score 0.04
- age at first sexual intercourse measurement · score 0.04
- non-melanoma skin carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3T2-F1 | alphafold | PREDICTED | 71.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3T2.
Amino-acid sequence (930 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SEMA6C?
The strongest Open Targets associations for SEMA6C are body mass index, age at menarche, cancer, monocyte count and osteoporosis.
How long is the SEMA6C protein?
The Homo sapiens SEMA6C protein (UniProt Q9H3T2) is 930 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3T2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3T2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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