Lysosomal dipeptide transporter MFSD1 (MFSD1)
Homo sapiens — UniProt Q9H3U5
Data last refreshed: (UniProt release unknown)
Key facts
Lysosomal dipeptide transporter MFSD1 (MFSD1) is a protein from Homo sapiens identified by UniProt accession Q9H3U5, 465 residues long. MolForge cross-references it against 0 known binders and 137 disease associations.
- UniProt accession: Q9H3U5; gene symbol MFSD1.
- Organism: Homo sapiens.
- Length: 465 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): insomnia measurement, blood protein measurement and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysosomal dipeptide transporter MFSD1 |
|---|---|
| UniProt accession | Q9H3U5 |
| Gene | MFSD1 |
| Organism | Homo sapiens |
| Length | 465 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (137)
Diseases linked to this target (Open Targets).
- insomnia measurement · score 0.25
- blood protein measurement · score 0.21
- systolic blood pressure · score 0.14
- neoplasm · score 0.08
- Congenital bile acid synthesis defect type 1 · score 0.05
- progressive familial intrahepatic cholestasis · score 0.05
- Hyperlipoproteinemia type 1 · score 0.05
- sideroblastic anemia 3 · score 0.05
- Isolated anophthalmia - microphthalmia · score 0.05
- Microphthalmia - ankyloblepharon - intellectual disability · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3U5-F1 | alphafold | PREDICTED | 88.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3U5.
Amino-acid sequence (465 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MFSD1?
The strongest Open Targets associations for MFSD1 are insomnia measurement, blood protein measurement, systolic blood pressure, neoplasm and Congenital bile acid synthesis defect type 1.
How long is the MFSD1 protein?
The Homo sapiens MFSD1 protein (UniProt Q9H3U5) is 465 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3U5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3U5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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