Membrane-spanning 4-domains subfamily A member 5 (MS4A5)
Homo sapiens — UniProt Q9H3V2
Data last refreshed: (UniProt release unknown)
Key facts
Membrane-spanning 4-domains subfamily A member 5 (MS4A5) is a protein from Homo sapiens identified by UniProt accession Q9H3V2, 200 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9H3V2; gene symbol MS4A5.
- Organism: Homo sapiens.
- Length: 200 amino acids.
- Top disease associations (Open Targets): blood protein measurement, ferritin measurement and HbA1c measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane-spanning 4-domains subfamily A member 5 |
|---|---|
| UniProt accession | Q9H3V2 |
| Gene | MS4A5 |
| Organism | Homo sapiens |
| Length | 200 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.12
- ferritin measurement · score 0.07
- HbA1c measurement · score 0.06
- cystatin C measurement · score 0.05
- platelet count · score 0.04
- Abnormal sperm morphology · score 0.01
- gastric cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3V2-F1 | alphafold | PREDICTED | 76.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3V2.
Amino-acid sequence (200 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MS4A5?
The strongest Open Targets associations for MS4A5 are blood protein measurement, ferritin measurement, HbA1c measurement, cystatin C measurement and platelet count.
How long is the MS4A5 protein?
The Homo sapiens MS4A5 protein (UniProt Q9H3V2) is 200 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3V2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3V2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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