Peptidase inhibitor R3HDML (R3HDML)
Homo sapiens — UniProt Q9H3Y0
Data last refreshed: (UniProt release unknown)
Key facts
Peptidase inhibitor R3HDML (R3HDML) is a protein from Homo sapiens identified by UniProt accession Q9H3Y0, 253 residues long. MolForge cross-references it against 0 known binders and 169 disease associations.
- UniProt accession: Q9H3Y0; gene symbol R3HDML.
- Organism: Homo sapiens.
- Length: 253 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, type 2 diabetes mellitus and hemoglobin A1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peptidase inhibitor R3HDML |
|---|---|
| UniProt accession | Q9H3Y0 |
| Gene | R3HDML |
| Organism | Homo sapiens |
| Length | 253 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (169)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.13
- type 2 diabetes mellitus · score 0.11
- hemoglobin A1 measurement · score 0.09
- mean reticulocyte volume · score 0.08
- Distal myopathy, Nonaka type · score 0.06
- myopathy · score 0.06
- inclusion body myositis · score 0.05
- GNE myopathy · score 0.05
- exercise intolerance, riboflavin-responsive · score 0.05
- tibial muscular dystrophy · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3Y0-F1 | alphafold | PREDICTED | 82.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3Y0.
Amino-acid sequence (253 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with R3HDML?
The strongest Open Targets associations for R3HDML are high density lipoprotein cholesterol measurement, type 2 diabetes mellitus, hemoglobin A1 measurement, mean reticulocyte volume and Distal myopathy, Nonaka type.
How long is the R3HDML protein?
The Homo sapiens R3HDML protein (UniProt Q9H3Y0) is 253 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3Y0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3Y0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.