Pancreatic progenitor cell differentiation and proliferation factor (PPDPF)
Homo sapiens — UniProt Q9H3Y8
Data last refreshed: (UniProt release unknown)
Key facts
Pancreatic progenitor cell differentiation and proliferation factor (PPDPF) is a protein from Homo sapiens identified by UniProt accession Q9H3Y8, 114 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q9H3Y8; gene symbol PPDPF.
- Organism: Homo sapiens.
- Length: 114 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, glomerular filtration rate and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pancreatic progenitor cell differentiation and proliferation factor |
|---|---|
| UniProt accession | Q9H3Y8 |
| Gene | PPDPF |
| Organism | Homo sapiens |
| Length | 114 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.24
- glomerular filtration rate · score 0.19
- creatinine measurement · score 0.19
- serum metabolite measurement · score 0.18
- schizophrenia · score 0.14
- glucose measurement · score 0.12
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.07
- non-alcoholic fatty liver disease · score 0.06
- Hepatic steatosis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H3Y8-F1 | alphafold | PREDICTED | 59.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H3Y8.
Amino-acid sequence (114 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPDPF?
The strongest Open Targets associations for PPDPF are neurodegenerative disease, glomerular filtration rate, creatinine measurement, serum metabolite measurement and schizophrenia.
How long is the PPDPF protein?
The Homo sapiens PPDPF protein (UniProt Q9H3Y8) is 114 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H3Y8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H3Y8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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