Kinetochore-associated protein DSN1 homolog (DSN1)
Homo sapiens — UniProt Q9H410
Data last refreshed: (UniProt release unknown)
Key facts
Kinetochore-associated protein DSN1 homolog (DSN1) is a protein from Homo sapiens identified by UniProt accession Q9H410, 356 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9H410; gene symbol DSN1.
- Organism: Homo sapiens.
- Length: 356 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, hepatocellular carcinoma and hair color.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kinetochore-associated protein DSN1 homolog |
|---|---|
| UniProt accession | Q9H410 |
| Gene | DSN1 |
| Organism | Homo sapiens |
| Length | 356 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.14
- hepatocellular carcinoma · score 0.03
- hair color · score 0.02
- sunburn · score 0.02
- carcinoma · score 0.02
- cervical squamous intraepithelial neoplasia · score 0.01
- neoplasm · score 0.01
- adenoma · score 0.01
- colorectal adenoma · score 0.01
- polyp · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H410-F1 | alphafold | PREDICTED | 67.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H410.
Amino-acid sequence (356 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DSN1?
The strongest Open Targets associations for DSN1 are appendicular lean mass, hepatocellular carcinoma, hair color, sunburn and carcinoma.
How long is the DSN1 protein?
The Homo sapiens DSN1 protein (UniProt Q9H410) is 356 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H410 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H410 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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