Uncharacterized protein C1orf198 (C1orf198)
Homo sapiens — UniProt Q9H425
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C1orf198 (C1orf198) is a protein from Homo sapiens identified by UniProt accession Q9H425, 327 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q9H425; gene symbol C1orf198.
- Organism: Homo sapiens.
- Length: 327 amino acids.
- Top disease associations (Open Targets): venous thromboembolism, neurodegenerative disease and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C1orf198 |
|---|---|
| UniProt accession | Q9H425 |
| Gene | C1orf198 |
| Organism | Homo sapiens |
| Length | 327 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- venous thromboembolism · score 0.32
- neurodegenerative disease · score 0.29
- protein measurement · score 0.17
- mean platelet volume · score 0.10
- body height · score 0.09
- transient myeloproliferative syndrome · score 0.04
- neutrophil immunodeficiency syndrome · score 0.04
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- combined immunodeficiency with skin granulomas · score 0.03
- chronic myelogenous leukemia · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H425-F1 | alphafold | PREDICTED | 60.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H425.
Amino-acid sequence (327 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1orf198?
The strongest Open Targets associations for C1orf198 are venous thromboembolism, neurodegenerative disease, protein measurement, mean platelet volume and body height.
How long is the C1orf198 protein?
The Homo sapiens C1orf198 protein (UniProt Q9H425) is 327 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H425 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H425 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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