Regulating synaptic membrane exocytosis protein 4 (RIMS4)
Homo sapiens — UniProt Q9H426
Data last refreshed: (UniProt release unknown)
Key facts
Regulating synaptic membrane exocytosis protein 4 (RIMS4) is a protein from Homo sapiens identified by UniProt accession Q9H426, 269 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H426; gene symbol RIMS4.
- Organism: Homo sapiens.
- Length: 269 amino acids.
- Top disease associations (Open Targets): diet measurement, breakfast skipping measurement and jaw disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Regulating synaptic membrane exocytosis protein 4 |
|---|---|
| UniProt accession | Q9H426 |
| Gene | RIMS4 |
| Organism | Homo sapiens |
| Length | 269 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.28
- breakfast skipping measurement · score 0.21
- jaw disease · score 0.15
- breast carcinoma · score 0.04
- self reported educational attainment · score 0.03
- colorectal adenocarcinoma · score 0.03
- blood protein measurement · score 0.02
- ulcerative colitis · score 0.02
- Crohn's disease · score 0.01
- colorectal cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H426-F1 | alphafold | PREDICTED | 71.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H426.
Amino-acid sequence (269 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RIMS4?
The strongest Open Targets associations for RIMS4 are diet measurement, breakfast skipping measurement, jaw disease, breast carcinoma and self reported educational attainment.
How long is the RIMS4 protein?
The Homo sapiens RIMS4 protein (UniProt Q9H426) is 269 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H426 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H426 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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