Potassium channel subfamily K member 15 (KCNK15)
Homo sapiens — UniProt Q9H427
Data last refreshed: (UniProt release unknown)
Key facts
Potassium channel subfamily K member 15 (KCNK15) is a protein from Homo sapiens identified by UniProt accession Q9H427, 330 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H427; gene symbol KCNK15.
- Organism: Homo sapiens.
- Length: 330 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, blood protein measurement and cutaneous melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Potassium channel subfamily K member 15 |
|---|---|
| UniProt accession | Q9H427 |
| Gene | KCNK15 |
| Organism | Homo sapiens |
| Length | 330 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.19
- blood protein measurement · score 0.14
- cutaneous melanoma · score 0.12
- pachyonychia congenita · score 0.08
- jaw disease · score 0.06
- hepatocellular carcinoma · score 0.04
- Tetralogy of Fallot · score 0.02
- diet measurement · score 0.02
- papillary thyroid carcinoma · score 0.02
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H427-F1 | alphafold | PREDICTED | 79.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H427.
Amino-acid sequence (330 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCNK15?
The strongest Open Targets associations for KCNK15 are lung adenocarcinoma, blood protein measurement, cutaneous melanoma, pachyonychia congenita and jaw disease.
How long is the KCNK15 protein?
The Homo sapiens KCNK15 protein (UniProt Q9H427) is 330 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H427 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H427 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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