RWD domain-containing protein 1 (RWDD1)
Homo sapiens — UniProt Q9H446
Data last refreshed: (UniProt release unknown)
Key facts
RWD domain-containing protein 1 (RWDD1) is a protein from Homo sapiens identified by UniProt accession Q9H446, 243 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9H446; gene symbol RWDD1.
- Organism: Homo sapiens.
- Length: 243 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Red cell distribution width and sitting height measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RWD domain-containing protein 1 |
|---|---|
| UniProt accession | Q9H446 |
| Gene | RWDD1 |
| Organism | Homo sapiens |
| Length | 243 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- Red cell distribution width · score 0.27
- sitting height measurement · score 0.08
- retinitis pigmentosa and erythrocytic microcytosis · score 0.04
- 22q11.2 deletion syndrome · score 0.03
- malaria · score 0.03
- ghosal hematodiaphyseal dysplasia · score 0.03
- Subcutaneous Panniculitis-Like T-Cell Lymphoma · score 0.03
- immunodeficiency 80 with or without congenital cardiomyopathy · score 0.03
- megaloblastic anemia, folate-responsive · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H446-F1 | alphafold | PREDICTED | 81.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H446.
Amino-acid sequence (243 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RWDD1?
The strongest Open Targets associations for RWDD1 are neurodegenerative disease, Red cell distribution width, sitting height measurement, retinitis pigmentosa and erythrocytic microcytosis and 22q11.2 deletion syndrome.
How long is the RWDD1 protein?
The Homo sapiens RWDD1 protein (UniProt Q9H446) is 243 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H446 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H446 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.