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CUE domain-containing protein 2 (CUEDC2)

Homo sapiens — UniProt Q9H467

Gene: CUEDC2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

CUE domain-containing protein 2 (CUEDC2) is a protein from Homo sapiens identified by UniProt accession Q9H467, 287 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.

  • UniProt accession: Q9H467; gene symbol CUEDC2.
  • Organism: Homo sapiens.
  • Length: 287 amino acids.
  • Top disease associations (Open Targets): erythrocyte count, creatinine measurement and neoplasm.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCUE domain-containing protein 2
UniProt accessionQ9H467
GeneCUEDC2
OrganismHomo sapiens
Length287 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (66)

Diseases linked to this target (Open Targets).

  • erythrocyte count · score 0.16
  • creatinine measurement · score 0.15
  • neoplasm · score 0.10
  • triple-negative breast cancer · score 0.07
  • acute myeloid leukemia · score 0.07
  • ovarian serous carcinoma · score 0.06
  • Autosomal recessive early-onset inflammatory bowel disease · score 0.04
  • self reported educational attainment · score 0.04
  • lymph node metastatic carcinoma · score 0.04
  • drug use measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H467-F1alphafoldPREDICTED72.46—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H467.

Amino-acid sequence (287 residues)

MELERIVSAA LLAFVQTHLP EADLSGLDEV IFSYVLGVLE DLGPSGPSEE NFDMEAFTEM MEAYVPGFAH IPRGTIGDMM QKLSGQLSDA RNKENLQPQS SGVQGQVPIS PEPLQRPEML KEETRSSAAA AADTQDEATG AEEELLPGVD VLLEVFPTCS VEQAQWVLAK ARGDLEEAVQ MLVEGKEEGP AAWEGPNQDL PRRLRGPQKD ELKSFILQKY MMVDSAEDQK IHRPMAPKEA PKKLIRYIDN QVVSTKGERF KDVRNPEAEE MKATYINLKP ARKYRFH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CUEDC2?

The strongest Open Targets associations for CUEDC2 are erythrocyte count, creatinine measurement, neoplasm, triple-negative breast cancer and acute myeloid leukemia.

How long is the CUEDC2 protein?

The Homo sapiens CUEDC2 protein (UniProt Q9H467) is 287 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H467
GeneCUEDC2
OrganismHomo sapiens
Length287
Binders0
Diseases66
View on UniProt