F-box/LRR-repeat protein 15 (FBXL15)
Homo sapiens — UniProt Q9H469
Data last refreshed: (UniProt release unknown)
Key facts
F-box/LRR-repeat protein 15 (FBXL15) is a protein from Homo sapiens identified by UniProt accession Q9H469, 300 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H469; gene symbol FBXL15.
- Organism: Homo sapiens.
- Length: 300 amino acids.
- Top disease associations (Open Targets): MODY, hyperproinsulinemia and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box/LRR-repeat protein 15 |
|---|---|
| UniProt accession | Q9H469 |
| Gene | FBXL15 |
| Organism | Homo sapiens |
| Length | 300 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- MODY · score 0.07
- hyperproinsulinemia · score 0.05
- mean corpuscular volume · score 0.05
- creatinine measurement · score 0.04
- Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.04
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04
- self reported educational attainment · score 0.04
- diabetes mellitus, permanent neonatal 4 · score 0.03
- diabetes mellitus, transient neonatal, 3 · score 0.03
- transient neonatal diabetes mellitus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H469-F1 | alphafold | PREDICTED | 89.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H469.
Amino-acid sequence (300 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXL15?
The strongest Open Targets associations for FBXL15 are MODY, hyperproinsulinemia, mean corpuscular volume, creatinine measurement and Glycogen storage disease due to hepatic glycogen synthase deficiency.
How long is the FBXL15 protein?
The Homo sapiens FBXL15 protein (UniProt Q9H469) is 300 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H469 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H469 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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