Torsin-3A (TOR3A)
Homo sapiens — UniProt Q9H497
Data last refreshed: (UniProt release unknown)
Key facts
Torsin-3A (TOR3A) is a protein from Homo sapiens identified by UniProt accession Q9H497, 397 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9H497; gene symbol TOR3A.
- Organism: Homo sapiens.
- Length: 397 amino acids.
- Top disease associations (Open Targets): body height, arterial stiffness measurement and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Torsin-3A |
|---|---|
| UniProt accession | Q9H497 |
| Gene | TOR3A |
| Organism | Homo sapiens |
| Length | 397 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- body height · score 0.08
- arterial stiffness measurement · score 0.08
- type 2 diabetes mellitus · score 0.06
- benign neoplasm of adrenal gland · score 0.04
- osteosarcoma · score 0.01
- ulcerative colitis · score 0.01
- neoplasm · score 0.01
- breast carcinoma · score 0.00
- nervous system disease · score 0.00
- psoriasis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H497-F1 | alphafold | PREDICTED | 77.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H497.
Amino-acid sequence (397 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TOR3A?
The strongest Open Targets associations for TOR3A are body height, arterial stiffness measurement, type 2 diabetes mellitus, benign neoplasm of adrenal gland and osteosarcoma.
How long is the TOR3A protein?
The Homo sapiens TOR3A protein (UniProt Q9H497) is 397 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H497 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H497 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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