Aminopeptidase B (RNPEP)
Homo sapiens — UniProt Q9H4A4
Data last refreshed: (UniProt release unknown)
Key facts
Aminopeptidase B (RNPEP) is a protein from Homo sapiens identified by UniProt accession Q9H4A4, 650 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q9H4A4; gene symbol RNPEP.
- Organism: Homo sapiens.
- Length: 650 amino acids.
- Top disease associations (Open Targets): blood protein measurement, urinary metabolite measurement and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Aminopeptidase B |
|---|---|
| UniProt accession | Q9H4A4 |
| Gene | RNPEP |
| Organism | Homo sapiens |
| Length | 650 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.30
- urinary metabolite measurement · score 0.24
- protein measurement · score 0.23
- butyrylcholinesterase measurement · score 0.22
- acute myeloid leukemia · score 0.09
- myelodysplastic syndrome · score 0.07
- matrix metalloproteinase 7 measurement · score 0.06
- neoplasm · score 0.06
- metabolite measurement · score 0.06
- Miyoshi myopathy · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4A4-F1 | alphafold | PREDICTED | 94.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4A4.
Amino-acid sequence (650 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNPEP?
The strongest Open Targets associations for RNPEP are blood protein measurement, urinary metabolite measurement, protein measurement, butyrylcholinesterase measurement and acute myeloid leukemia.
How long is the RNPEP protein?
The Homo sapiens RNPEP protein (UniProt Q9H4A4) is 650 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4A4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4A4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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