Golgi phosphoprotein 3-like (GOLPH3L)
Homo sapiens — UniProt Q9H4A5
Data last refreshed: (UniProt release unknown)
Key facts
Golgi phosphoprotein 3-like (GOLPH3L) is a protein from Homo sapiens identified by UniProt accession Q9H4A5, 285 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q9H4A5; gene symbol GOLPH3L.
- Organism: Homo sapiens.
- Length: 285 amino acids.
- Top disease associations (Open Targets): lymphocyte count, neutrophil percentage of leukocytes and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi phosphoprotein 3-like |
|---|---|
| UniProt accession | Q9H4A5 |
| Gene | GOLPH3L |
| Organism | Homo sapiens |
| Length | 285 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.23
- neutrophil percentage of leukocytes · score 0.20
- prostate carcinoma · score 0.18
- eosinophil count · score 0.17
- platelet count · score 0.14
- cancer · score 0.14
- chronotype measurement · score 0.12
- forced expiratory volume · score 0.12
- coffee consumption measurement · score 0.12
- vital capacity · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4A5-F1 | alphafold | PREDICTED | 84.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4A5.
Amino-acid sequence (285 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GOLPH3L?
The strongest Open Targets associations for GOLPH3L are lymphocyte count, neutrophil percentage of leukocytes, prostate carcinoma, eosinophil count and platelet count.
How long is the GOLPH3L protein?
The Homo sapiens GOLPH3L protein (UniProt Q9H4A5) is 285 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4A5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4A5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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