Golgi phosphoprotein 3 (GOLPH3)
Homo sapiens — UniProt Q9H4A6
Data last refreshed: (UniProt release unknown)
Key facts
Golgi phosphoprotein 3 (GOLPH3) is a protein from Homo sapiens identified by UniProt accession Q9H4A6, 298 residues long. MolForge cross-references it against 0 known binders and 226 disease associations.
- UniProt accession: Q9H4A6; gene symbol GOLPH3.
- Organism: Homo sapiens.
- Length: 298 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, urinary bladder carcinoma and esophageal squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi phosphoprotein 3 |
|---|---|
| UniProt accession | Q9H4A6 |
| Gene | GOLPH3 |
| Organism | Homo sapiens |
| Length | 298 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (226)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.21
- urinary bladder carcinoma · score 0.21
- esophageal squamous cell carcinoma · score 0.21
- lung adenocarcinoma · score 0.21
- melanoma · score 0.20
- body height · score 0.19
- cutaneous melanoma · score 0.19
- pancreatic ductal adenocarcinoma · score 0.19
- acute myeloid leukemia · score 0.19
- breast carcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4A6-F1 | alphafold | PREDICTED | 83.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4A6.
Amino-acid sequence (298 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GOLPH3?
The strongest Open Targets associations for GOLPH3 are hepatocellular carcinoma, urinary bladder carcinoma, esophageal squamous cell carcinoma, lung adenocarcinoma and melanoma.
How long is the GOLPH3 protein?
The Homo sapiens GOLPH3 protein (UniProt Q9H4A6) is 298 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4A6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4A6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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