Dipeptidase 2 (DPEP2)
Homo sapiens — UniProt Q9H4A9
Data last refreshed: (UniProt release unknown)
Key facts
Dipeptidase 2 (DPEP2) is a protein from Homo sapiens identified by UniProt accession Q9H4A9, 486 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q9H4A9; gene symbol DPEP2.
- Organism: Homo sapiens.
- Length: 486 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, alcohol drinking and alcohol consumption measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dipeptidase 2 |
|---|---|
| UniProt accession | Q9H4A9 |
| Gene | DPEP2 |
| Organism | Homo sapiens |
| Length | 486 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.23
- alcohol drinking · score 0.19
- alcohol consumption measurement · score 0.18
- cutaneous melanoma · score 0.13
- head and neck squamous cell carcinoma · score 0.11
- lung adenocarcinoma · score 0.10
- uric acid measurement · score 0.09
- BMI-adjusted waist-hip ratio · score 0.08
- refractive error · score 0.07
- urate measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4A9-F1 | alphafold | PREDICTED | 82.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4A9.
Amino-acid sequence (486 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DPEP2?
The strongest Open Targets associations for DPEP2 are high density lipoprotein cholesterol measurement, alcohol drinking, alcohol consumption measurement, cutaneous melanoma and head and neck squamous cell carcinoma.
How long is the DPEP2 protein?
The Homo sapiens DPEP2 protein (UniProt Q9H4A9) is 486 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4A9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4A9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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