Band 4.1-like protein 1 (EPB41L1)
Homo sapiens — UniProt Q9H4G0
Data last refreshed: (UniProt release unknown)
Key facts
Band 4.1-like protein 1 (EPB41L1) is a protein from Homo sapiens identified by UniProt accession Q9H4G0, 881 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9H4G0; gene symbol EPB41L1.
- Organism: Homo sapiens.
- Length: 881 amino acids.
- Top disease associations (Open Targets): intellectual disability, autosomal dominant, autosomal dominant non-syndromic intellectual disability and BMI-adjusted hip circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Band 4.1-like protein 1 |
|---|---|
| UniProt accession | Q9H4G0 |
| Gene | EPB41L1 |
| Organism | Homo sapiens |
| Length | 881 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- intellectual disability, autosomal dominant · score 0.40
- autosomal dominant non-syndromic intellectual disability · score 0.37
- BMI-adjusted hip circumference · score 0.28
- Abnormal brain morphology · score 0.27
- thyroid gland adenocarcinoma · score 0.25
- keratinocyte carcinoma · score 0.22
- body height · score 0.20
- anthropometric measurement · score 0.19
- hair colour measurement · score 0.19
- appendicular lean mass · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4G0-F1 | alphafold | PREDICTED | 61.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4G0.
Amino-acid sequence (881 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EPB41L1?
The strongest Open Targets associations for EPB41L1 are intellectual disability, autosomal dominant, autosomal dominant non-syndromic intellectual disability, BMI-adjusted hip circumference, Abnormal brain morphology and thyroid gland adenocarcinoma.
How long is the EPB41L1 protein?
The Homo sapiens EPB41L1 protein (UniProt Q9H4G0) is 881 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4G0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4G0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.