Cystatin-9-like (CST9L)
Homo sapiens — UniProt Q9H4G1
Data last refreshed: (UniProt release unknown)
Key facts
Cystatin-9-like (CST9L) is a protein from Homo sapiens identified by UniProt accession Q9H4G1, 147 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q9H4G1; gene symbol CST9L.
- Organism: Homo sapiens.
- Length: 147 amino acids.
- Top disease associations (Open Targets): cystatin C measurement, neurodegenerative disease and benign prostatic hyperplasia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cystatin-9-like |
|---|---|
| UniProt accession | Q9H4G1 |
| Gene | CST9L |
| Organism | Homo sapiens |
| Length | 147 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- cystatin C measurement · score 0.37
- neurodegenerative disease · score 0.30
- benign prostatic hyperplasia · score 0.06
- Testicular regression syndrome · score 0.05
- 46,XX ovotesticular disorder of sex development · score 0.04
- major depressive disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4G1-F1 | alphafold | PREDICTED | 86.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4G1.
Amino-acid sequence (147 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CST9L?
The strongest Open Targets associations for CST9L are cystatin C measurement, neurodegenerative disease, benign prostatic hyperplasia, Testicular regression syndrome and 46,XX ovotesticular disorder of sex development.
How long is the CST9L protein?
The Homo sapiens CST9L protein (UniProt Q9H4G1) is 147 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4G1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4G1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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