Zinc fingers and homeoboxes protein 3 (ZHX3)
Homo sapiens — UniProt Q9H4I2
Data last refreshed: (UniProt release unknown)
Key facts
Zinc fingers and homeoboxes protein 3 (ZHX3) is a protein from Homo sapiens identified by UniProt accession Q9H4I2, 956 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.
- UniProt accession: Q9H4I2; gene symbol ZHX3.
- Organism: Homo sapiens.
- Length: 956 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, low density lipoprotein cholesterol measurement and bilirubin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc fingers and homeoboxes protein 3 |
|---|---|
| UniProt accession | Q9H4I2 |
| Gene | ZHX3 |
| Organism | Homo sapiens |
| Length | 956 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (111)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.43
- low density lipoprotein cholesterol measurement · score 0.40
- bilirubin measurement · score 0.39
- hair shape measurement · score 0.37
- balding measurement · score 0.36
- alcohol drinking · score 0.35
- bone quantitative ultrasound measurement · score 0.35
- blood phosphate measurement · score 0.34
- alkaline phosphatase measurement · score 0.34
- bone density · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4I2-F1 | alphafold | PREDICTED | 59.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4I2.
Amino-acid sequence (956 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZHX3?
The strongest Open Targets associations for ZHX3 are heel bone mineral density, low density lipoprotein cholesterol measurement, bilirubin measurement, hair shape measurement and balding measurement.
How long is the ZHX3 protein?
The Homo sapiens ZHX3 protein (UniProt Q9H4I2) is 956 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4I2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4I2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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