TraB domain-containing protein (TRABD)
Homo sapiens — UniProt Q9H4I3
Data last refreshed: (UniProt release unknown)
Key facts
TraB domain-containing protein (TRABD) is a protein from Homo sapiens identified by UniProt accession Q9H4I3, 376 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9H4I3; gene symbol TRABD.
- Organism: Homo sapiens.
- Length: 376 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, platelet count and platelet crit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TraB domain-containing protein |
|---|---|
| UniProt accession | Q9H4I3 |
| Gene | TRABD |
| Organism | Homo sapiens |
| Length | 376 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- platelet count · score 0.27
- platelet crit · score 0.25
- eosinophil count · score 0.24
- mean platelet volume · score 0.23
- liver fibrosis measurement · score 0.20
- mitochondrial DNA measurement · score 0.20
- eosinophil percentage of leukocytes · score 0.19
- platelet-to-lymphocyte ratio · score 0.16
- triglyceride measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4I3-F1 | alphafold | PREDICTED | 80.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4I3.
Amino-acid sequence (376 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRABD?
The strongest Open Targets associations for TRABD are neurodegenerative disease, platelet count, platelet crit, eosinophil count and mean platelet volume.
How long is the TRABD protein?
The Homo sapiens TRABD protein (UniProt Q9H4I3) is 376 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4I3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4I3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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